The “ecstasy” hangover: hyponatremia due to 3,4-methylenedioxymethamphetamine

And a third study, also unpublished, strengthens that link by screening out the effects of other drugs such as LSD, amphetamines and cannabis. Michael Morgan and his colleagues at the University of Wales, Swansea, compared two groups of Welsh drug users with a control group of people the same age. The two drug groups matched each other for consumption of most drugs, but only one took Ecstasy. In most tests, the three groups performed similarly, indicating that Ecstasy users are no less intelligent than the norm.

Researchers say some people may end up with drinking problems because they drink in an effort to relieve hangover symptoms. Regular abuse of MDMA also appears to change how the brain produces and responds to serotonin, and it changes the dopamine system, which is tied to the brain’s reward pathways. This can increase impulsive behaviors, including compulsions around drugs or alcohol. It increases the risk of mood disorders such as depression and anxiety, which, in turn, increases the risk of self-medicating with drugs and alcohol. Keeping your brain occupied during an MDMA hangover will really help to stop you from dwelling on feelings of depression, anxiety, and unease. Going for a hike with friends is an excellent choice, especially along trails.

• In fact, none of the ingredients in the supplements have been tested on MDMA or alcohol users.
• Drugs cause damage because they increase the production of poisonous free radicals.
• This comedown can often result in feelings of depression, sadness, and discontent.
• A publication within the journal Current Pharmaceutical Biotechnology discusses the association between acute and sub-chronic use of MDMA and oxidative stress.
• This method simply postpones the point in time when the blood alcohol concentration in your body returns to zero and your hangover peaks—but the moment will come anyway.

What are the symptoms of an MDMA hangover?

Taking additional vitamins is always a good idea, as well as keeping hydrated. Keep tabs on how much water you drink, however, as ecstasy is known to cause secretion of an antidiuretic hormone known as ADH and raise body temperature. Combine this with hot clubs and excessive water intake is very likely to happen.

Cocaine, MDMA, Ketamine: How to ease the come-down by drug experts

Taking too much MDMA is a sure-fire way to end up with a hangover. You don’t need much MDMA to feel its effects; it’s easy to push your body beyond its limits. Thus, it’s always prudent to start with a low dose and see how your body reacts.

MeSH terms

If you’re a regular coffee drinker and you feel like you need to, it’s recommended to have a small cup. But a month ago she discovered a supplement brand called Happy Tuesdays. Magnesium deficiency is not something that’s easily detectable, but it’s something very easily attainable, considering the diet of many Western World citizens.

• Most notably, the almost compulsive need to dance while on the drug, the sense of openness and connectedness with the user’s surroundings were the effects that won over the young user base.
• Let your mind and body guide you—a carb-heavy meal in your favourite form may end up being incredibly comforting.
• Reactive oxygen species are highly reactive molecules that can damage cell structures.
• If you’ve indulged or overindulged in alcohol or certain other mind-altering substances, your liver may well need a little support.
• Although MDMA has a harsh comedown, many users argue that the experience is worth it.

MDMA carries risks of both dehydration and overhydration. If fluids aren’t replaced to cool the body, then heat stroke can occur. However, MDMA can also cause the body to retain water at the cellular level, meaning consuming too much water can cause an imbalance between water and sodium in the blood. Although MDMA has a harsh comedown, many users argue that the experience is worth it. But MDMA offers people an opportunity to really drop their mask and connect with others, resulting in rare and memorable experiences.

✅ Eat a carb-heavy breakfast

Caffeine may not have any special anti-hangover powers, but as a stimulant, it could help with the grogginess. Experiments have shown that clear liquors, such as vodka and gin, tend to cause hangovers less frequently than dark ones, such as whiskey, red wine, and tequila. The main form of alcohol in alcoholic beverages is ethanol, but the darker liquors contain chemically related compounds (congeners), including methanol. The same enzymes process ethanol and methanol, but methanol metabolites are especially toxic, so they may cause a worse hangover. Drinking interferes with brain activity during sleep, so a hangover may be a form of sleep deprivation.

So is there a way to avoid this unwanted sensation? While most party-going molly-loving souls have experienced this problem, many have not. Namely, different mdma hangover cure dosage intakes and different levels of magnesium in the body. As the existence of the hangover suggests, MDMA is hard on you.

This kicks our nervous system into high gear, leaving us tired and depleted the next day. To recover, we need to build back our reserves of neurotransmitters, and address the oxidative stress (toxicity) caused by the previous night’s chemical overload. Actual hangover symptoms can last for up to 24 hours, and peak when the blood alcohol concentration in the body gets back to zero. However, the aftermath of (over)indulging can last much longer than that—you may feel physically unwell for days after.

Long-Term Abuse Damages the Brain

Obviously, not drinking any alcohol is the best solution. But if you do drink, here are simple tips to help prevent and relieve the misery. If untreated, severe dehydration can also cause low blood volume, kidney damage and failure, heat injury, and seizures. For the most part, ecstasy, MDMA, and Molly are ingested orally. Ecstasy is most often found in tablet form, while Molly may be found in powdered form and mixed with water, juice, or alcohol. It is rarely smoked or injected, although these forms of ingestion have occasionally occurred.

Magnesium supplements are really a step in the right direction, but the way they’re being taken, as well as which type of supplements is being taken, is also something to pay attention to. Taking a supplement dosage on the day you’re planning to go out to party with Molly is very unlikely to give you any result. The supplements should be taken systematically, meaning a routine should be implemented.

This method simply postpones the point in time when the blood alcohol concentration in your body returns to zero and your hangover peaks—but the moment will come anyway. And if you choose the same “cure”, then you can imagine how it’ll continue. If your head is giving you a particularly hard time, even after all that water and some food, some painkillers may come in handy. As nonsteroidal anti-inflammatory drugs (NSAIDs), ibuprofen and aspirin are popular over-the-counter pain medications that people use for hangovers, too.